Research & Clinical Trials

Research Studies

ADD/ADHD

1. Do You Have ADD/ADHD?
Men and women ages who have been diagnosed with ADD or ADHD are needed for a two-day outpatient study at the Johns Hopkins University School of Medicine in Baltimore, Maryland. Volunteers with ADHD who have used medications for the treatment of ADHD and those who have never used medications for the treatment of ADHD are needed.

Volunteers should be between the ages of 18 and 40 and in general good health. Testing will take place at the Johns Hopkins Hospital and Johns Hopkins Bayview Medical Center. Study participants will receive compensation, and travel expenses will be covered. Earn up to $300 plus travel expenses.

For more information, call 410-550-2588 or 410-550-5295 or e-mail johnshopkins.lab@gmail.com.

Collect calls are accepted.

Principal Investigator: Una D. McCann, MD
IRB Number: NA_00033609
05.21.2010

Aging

1. Are You 70 Years of Age or Older?
Investigators from the Division of Geriatric Medicine at Johns Hopkins are looking for individuals, aged 70 years or older, to participate in a research study looking at the aging process.

Tests would include measurements of strength, walking speed and questions about your physical activities. We also request a blood draw.

You willl be paid $10 for participating. The study can be done in your home. Or, if you choose to travel to the Medical Center, your parking costs will be covered.

For more information, please call 410-550-2113.

PI: Jeremy Walston, M.D.
AAC 98-10-14-01
11.18.2008

2. Are you between the ages of 20 and 30? Are you interested in medical research?
Investigators from the Division of Geriatric Medicine at Johns Hopkins are looking for healthy individuals, ages 20 to 30, to participate in a research study that will identify the differences in hormone and immune system cells between younger and older individuals.

Participation involves answering a questionaire about your medical history and a blood draw.

You will be paid $10 for participating. Your parking costs will be covered.

For more information, please call 410-550-2113.

PI: Jeremy Walston, M.D.
AAC 98-10-14-01
11.18.2008

3. Are You 70 Years or Older?
Investigators from the Division of Geriatric Medicine at Johns Hopkins are looking for individuals, aged 70 years or older, to participate in a research study looking at the effects of nutritional supplements on aging.

Screening questions will be asked regarding your health and physical activity. If you're eligible, we will ask you to donate a blood sample. Based on these results, we may ask you to participate in a more detailed study of nutritional supplementation. Home visits are available if you cannot come to Johns Hopkins Bayview. Upon completion of the study, you will be paid $50.

For more information, please call 410-550-2113.

PI: Jeremy Walston, M.D.
Protocol: NA_00002109
11.18.2008

4. Are You Over 60 and Feeling Depressed?
Are you over 60 and feeling depressed? Symptoms of depression in older adults are common yet often go undetected. They could include feelings of sadness or hopelessness, loss of energy, inability to enjoy pleasurable activities, changes in appetite or sleeping patterns, or poor concentration/memory.

If you are feeling depressed, not taking antidepressant medication and in good physical health you may be eligible to participate in a research study involving treatment. Qualified people will participate at no cost to them and will be compensated for their time and transportation.

For more information about the research study, please call us at 410-550-9052 or email us at cworkma3@jhmi.edu. Click here for a flyer (PDF).

Principal Investigator: Gwenn Smith, Ph.D.
NA_000021615
01.11.2010

5. Are You Over 60 and Interested In Research?
We are conducting brain imaging research using a technique called Positron Emission Tomography, or PET for short, to take pictures of the brain. If you are in good health and aren’t taking medications that affect the brain, you may qualify for participation. Qualified people will participate at no cost to them. Compensation for time and transportation will be provided.

For more information, please call 410-550-9052. Click here for a flyer (PDF).

Principal Investigator: Gwenn Smith, Ph.D.
NA_000021615
01.11.2010

Anxiety/Depression

1. Struggling with Anxiety? Worried about your child developing anxiety?
Researchers at Johns Hopkins are seeking mothers who struggle with anxiety and have a child between the ages of 7 and 12 to participate in a prevention study for child anxiety. Qualified participants will receive a free evaluation and may be paid for completing the one-year study. Qualified families may also be eligible to receive an 8-week prevention program with possible benefits of improved parenting skills, coping skills, and family knowledge and communication about anxiety.

Inf Golda Ginsberg, Ph.D. at (443) 287-4349.
08.27.2008

2. Participants Needed for a Research Study on Child Distress and Coping when Parents Must Give Injections to their Children
Children ages 2-10 years with Diabetes, Growth Hormone Deficiency or other Medical Condition requiring injections given daily or weekly by a parent (or other caregiver) are needed. This study is attempting to learn about what causes some children to develop a lot of distress and anxiety when a parent (or other family caregiver) gives injections while other children do not have a lot of anxiety and distress. Children and parents who participate will be observed and videotaped during up to four visits to the Pediatric Psychology Clinic. The filming will be done during a non-medical play activity and while the caregiver gives injections as prescribed by your child's doctor. Parents will be asked to complete questionnaires about their child's and their own behavior, anxiety and distress. Total time for participation will be up to four no charge clinic visits lasting about 50 minutes each. Gift certificates will be given to the child for each visit and to parents at the end of the final session.

If you are interested or have questions, please call Project Coordinator, Melissa Beck, Ph.D., at 443-923-2900.

Principal Investigator: Keith J. Slifer, Ph.D., The Kennedy Krieger Institute.
08.27.2008

3. Attention Parents!
Experts at the Kennedy Krieger Institute are recruiting children, age 8 to 12, to participate in a research study investigating the brain pathways involved in childhood anxiety disorders. The study will include a psychological assessment and a magnetic resonance imaging (MRI) scan of the brain. The entire study takes about six hours and can be done in two to three visits, whichever is more convenient.

There are no major risks associated with this study. Participants will be compensated with $100, a small gift and free parking. Call 443-923-2643 or e-mail vasa@kennedykrieger.org.

PI: Roma Vasa, M.D.
NA_00003215
08.07.2008

For more information about the research study, please call us at 410-550-9052 or email us at cworkma3@jhmi.edu. Click here for a flyer (PDF).

Principal Investigator: Gwenn Smith, Ph.D.
NA_000021615
01.11.2010

5. Child Gaining Weight on Medication?
Mark Riddle, M.D., and colleagues in the Johns Hopkins Division of Child and Adolescent Psychiatry are conducting a treatment research study funded by the National Institute of Mental Health. The goal of the study is to find improved treatments for youth who have a have gained weight while taking antipsychotic medication.

We are currently seeking children ages 8-19 who are taking olanzapine (Zyprexa®), quetiapine (Seroquel®), risperidone (Risperdal®), aripiprazole (Abilify®), or ziprasidone (Geodone®) and have gained a significant amount of weight in the past year while taking one of these medications. Consenting children who meet eligibility criteria will receive a medical and psychiatric evaluation and will be assigned to one of three groups: 1) stay on current medication, 2) switch from current medication to aripiprazole (Abilify®) or perphenazine (Trilafon®), 3) stay on current medication and add metformin (Glucophage®). Participants receive study-related evaluations and treatment at no cost.

For further information, call 410-614-5174 or e-mail impact@jhu.edu.

PI: Mark Riddle, M.D.
IRB #00017204
05.27.2010

Arthritis

1. Do You Have Knee Arthritis?
Volunteers are needed for a sleep and sensory testing study. Researchers at The Johns Hopkins University School of Medicine are looking for volunteers to participate in a research study examining the association between sleep and sensory abilities in arthritis.

To participate in this study, you must:

Be 50 years of age or older;
Have osteoarthritis of the knee;
Have knee pain; and
Either have trouble sleeping or be a good sleeper.

This study involves:

Two sleep studies conducted in your home; and
Sensory testing at Johns Hopkins.

All examinations, parking and tests are provided at no cost. Participants will be compenstated up to $110.

For more information on the study or to see if you are eligible, please call 410-550-9057 or visit our Web site: www.sleeplessinbaltimore.com.

PI: Michael T. Smith, Ph.D.
Protocol: NA_00011802
05.19.2009

2. Do you have Knee Arthritis and Insomnia?
Volunteers are needed for a research study to evaluate a new sleeping medication in patients with osteoarthritis of the knee.

To participate in this study, you must :

Have knee arthritis;
Have trouble sleeping for at least 6 months; and
Be 18 to 64 years old.

Examinations, parking and study pills are provided at no cost. Participants will be compensated up to $300.

For more information on the study or to see if you are eligible, please call 410-550-7999 or visit our Web site: www.sleeplessinbaltimore.com.

PI: Michael T. Smith, Ph.D.
Protocol: NA_00001703
05.19.2009

Asthma/Allergy

1. Do you have allergies to cats, eggs, milk or peanuts?
Researchers at Johns Hopkins are looking for volunteers who are allergic to cats, milk, eggs or peanuts for ongoing and future studies at the Johns Hopkins Asthma & Allergy Center. You will be paid for study participation.

For more information or to apply, call 410-550-2200 or e-mail studies@jhmi.edu. For more ongoing allergy studies, visit www.hopkinsmedicine.org/allergy.

Principal Investigator: Bruce Bochner, M.D.
IRB# NA_00006137
01.12.2009

2. Researchers at Johns Hopkins Are Looking for Healthy Volunteers
No allergies? No asthma? Researchers at Johns Hopkins are looking for healthy volunteers for ongoing and future studies at the Johns Hopkins Asthma & Allergy Center. You will be paid for study participation.

For more information or to apply, call 410-550-2200 or e-mail studies@jhmi.edu. For more ongoing allergy studies, visit www.hopkinsmedicine.org/allergy.

Principal Investigator: Bruce Bochner, M.D.
IRB# NA_00006137
01.12.2009

3. Do you have asthma?
Do you have asthma? Researchers at Johns Hopkins are looking for volunteers with asthma for ongoing and future studies at the Johns Hopkins Asthma & Allergy Center. You will be paid for study participation.

For more information or to apply, call 410-550-2200 or e-mail studies@jhmi.edu. For more ongoing allergy studies, visit www.hopkinsmedicine.org/allergy.

Principal Investigator: Bruce Bochner, M.D.
IRB# NA_00006137
01.12.2009

4. Are you allergic to peanuts?
Researchers at Johns Hopkins are seeking adults (18+) with peanut allergy for a research study to treat peanut allergy. We will use an injectable drug that is FDA-approved for asthma. You will be compensated for participating in this 12-month study.

For more information, please call 410-926-4918 or e-mail peanutallergy@jhmi.edu.

PI: Robert Wood, M.D.
NA_00026397
07.24.2009

5. DO YOU SUFFER WITH FALL ALLERGIES? DO YOU HAVE RAGWEED ALLERGY IN AUGUST & SEPTEMBER?
The Johns Hopkins Asthma & Allergy Center is looking for volunteers to join an 18-month research study with 11 office visits. The study will test an experimental oral medicine for ragweed allergies.

Participants must be between 18 and 50 years of age, have fall ragweed allergies and not be on allergy shots. Participants will be paid for their time.

For more information or to enroll in the study, call 410-550-2122.

Principal Investigator: Peter S. Creticos, M.D.
NA_00031323
03.16.2010

6. DO YOU HAVE NASAL POLYPS?
The Johns Hopkins Asthma & Allergy Center is looking for volunteers to join an 18-week research study with six visits. The study will test an experimental nasal spray for nasal polyps.

Participants must be between 18 and 70 years of age, have nasal polyps and not be pregnant or breastfeeding. Participants will be paid for their time.

For more information or to enroll in the study, call 410-550-2122.

Principal Investigator: Peter S. Creticos, M.D.
NA_00029405
03.16.2010

Brain Imaging/Mapping

1. Volunteers Needed for Research on Brain Imaging of Cognitive Function
We are looking for people to participate in studies involving either fMRI (functional magnetic resonance imaging) or TMS (transcranial magnetic stimulation) or both.?Studies take between 1 hour to 4 hours total, and you will be compensated $20/hour for your time.

To be eligible to participate, you must:

be 60-70 years old;
be a native speaker of English (ie, have learned English before the age of 5);
be right handed;
have a social security number or taxpayer ID (so we can pay you!);
have no history of neurological disorders;
have no unremovable metal in your body (fillings in teeth are ok);
have no history of claustrophobia; or,
have no history of heart or respiratory disease, seizures or strokes (for TMS studies).

For more information on fMRI and/or TMS, log on to www.jhu.edu/nimlab. To participate in this study, call 410-502-5151.

Johns Hopkins Protocol Number: 05-06-01-03
Principal Investigator: John E. Desmond, Ph.D.
08.27.2008

2. Do you use cocaine, marijuana, ecstasy or heroin?
If so, you may be able to participate in research studies to see how drugs affect the body and brain. The studies take place in East Baltimore and are sponsored by the National Institute on Drug Abuse (NIDA), National Institutes of Health, U.S. Department of Health and Human Services.

You will be compensated for your time and travel.

Call 1-800-535-8254 from 8:30 a.m. to 8 p.m. for a confidential screening or visit www.researchstudies.drugabuse.gov.

11.18.2008

3. Do you smoke cigarettes?
If so, you may be able to participate in research studies to see how smoking affects the body and brain. The studies take place in East Baltimore and are sponsored by the National Institute on Drug Abuse (NIDA), National Institutes of Health, U.S. Department of Health and Human Services.

You will be compensated for your time and travel.

Call 1-800-535-8254 from 8:30 a.m. to 8 p.m. for a confidential screening or visit www.researchstudies.drugabuse.gov.

11.18.2008

Caffeine Use

1. Problematic Use Of Energy Drinks? Seeking Research Interviews with Children or Adolescents and Their Parents
Researchers at Johns Hopkins are seeking children and adolescents age 8-21 who have gotten sick or had unpleasant effects after consuming energy drinks (e.g., Red Bull, Monster, Rockstar, Full Throttle).

Study participation will involve a telephone interview with both child and a parent of the child.

Please call Jenna at 410-550-2687 or e-mail energydrinks@bpru.org.

Principal Investigator: Roland Griffiths, Ph.D.
NA_00016448
07.29.2010

Cancer

1. Seeking Volunteers with a Cancer Diagnosis to Participate in a Scientific Study of Self-Exploration and Personal Meaning
In recent years, scientists at some US universities have been conducting studies using entheogens, resuming research in pharmacology, psychology, creativity and spirituality that was suspended following the drug excesses of the 1960s.

Entheogens include the peyote cactus used by the Native American Church, the psilocybin-containing mushrooms used as sacraments in Mesoamerica, and certain other plants and chemicals. Such substances have been used for thousands of years in cultures from the Amazon to ancient Greece as a means of inducing non-ordinary states of consciousness for psychological self-exploration and spiritual or religious purposes.

These states of consciousness are most widely known in connection with practices such as meditation and prolonged fasting. Context seems to play a major role in shaping entheogen experiences and their consequences. Despite the well-known problems that can arise in unstructured settings, the risks of entheogens in research and ritual contexts have proven to be very small.

Researchers at The Johns Hopkins University School of Medicine are seeking volunteers with a current or past diagnosis of cancer who have some anxiety or are feeling down about their cancer to participate in a scientific study of self-exploration and personal meaning brought about by the entheogen psilocybin, a psychoactive substance found in mushrooms used as a sacrament in some cultures, given in a comfortable, supportive setting. Questionaires and interviews will be used to assess the effects of the substance on consciousness, mood and behavior.

Volunteers enrolled in the study will receive careful preparations and two sessions in which they will receive psilocybin. Structured guidance will be provided during the session and afterwards to facilitate integration of the experiences. The study complies with FDA regulations.

Volunteers must be between 21 and 70 years of age, have no personal history of severe psychiatric illness, or recent history of alcoholism or drug abuse, and have someone willing to pick them up and drive them home at the end of the two psilocybin sessions (around 5 p.m.).

For more detailed information about the study, visit bpru.org/cancer/insight. If you would like to discuss the possibility of volunteering, please call 410-550-5990 or e-mail cancer@bpru.org. Confidentiality will be maintained for all applicants and participants.

PI: Roland R. Griffiths, Ph.D.
Protocol: NA_00001390
07.29.2010

2. Do you have non-small cell lung cancer?
Researchers at Johns Hopkins are seeking individuals with non-small cell lung cancer to participate in a research project that studies how an investigational drug may affect weight gain and strength.

For more information, please call the Clinical Trials Unit at 410-502-3686 or e-mail myep1@jhmi.edu.

PI: Adrian S. Dobs, M.D., MHS
Protocol: NA_00018756
01.12.09

Commonly Used Medications

1. Have You Been Treated With Antibiotics?
Have you taken vancomycin, penicillin or amoxicillin for at least seven days within the past five years? OR, have you had an allergic reaction to these antibiotics within the past five years? Are you 18 to 70 years of age?

If so, you may be able to participate in a research study being done to learn why some people are allergic to certain antibiotics. The study involves two to four visits and two to four blood draws. Volunteers will be paid for their time.

Please call 410-550-2120.

Principal Investigator: N. Franklin Adkinson, M.D.
Study Number: NA_00014021
08.27.2008

2. Effects of Over-The-Counter Drugs on Mood and Preference
Healthy men and women, aged 18 to 65 who do not use tobacco products, are needed to participate in an outpatient research study of low doses of over-the-counter compounds found in drugs, food, herbal products and beverages.

The study is expected to last one to ten months and involves brief visits to Johns Hopkins Bayview Medical Center during weekdays.

You can earn up to $4,010 for participating.

For more information, please call 410-550-1916 and refer to study #0814.

PI: Roland Griffiths, Ph.D.
NA_00024382
07.29.2010

3. Child Gaining Weight on Medication?
Mark Riddle, M.D., and colleagues in the Johns Hopkins Division of Child and Adolescent Psychiatry are conducting a treatment research study funded by the National Institute of Mental Health. The goal of the study is to find improved treatments for youth who have a have gained weight while taking antipsychotic medication.

For further information, call 410-614-5174 or e-mail impact@jhu.edu.

PI: Mark Riddle, M.D.
IRB #00017204
05.27.2010

Diabetes

1. Do You Have Diabetes?
The Johns Hopkins Bayview Medical Center is conducting a study to find out if exercise reduces blood pressure and body fat, and improves fitness and cardiovascular health. If you have diabetes, are 40-65 years old and not smoking, you may be eligible. All visits are free, including parking, and qualified participants are eligible for additional compensation.

For more information, please call 410-550-5428/5429 or 410-550-5029.

RPN # 03-08-12-02
Principal investigator: Kerry J. Stewart, Ed.D.
08.27.2008

2. Diabetic Subjects Needed For a Noninvasive MRI Scan Before and After a 3-Week Course of a Common Cholesterol-Lowering Medicine
We are seeking diabetic subjects to participate in a study designed to improve the way problems with blood vessels are evaluated and treated.

There are three visits in four weeks. An FDA-approved cholesterol tablet will be taken daily for three weeks with blood samples and MRI scans of the arm and leg before and after taking the medicine.

To qualify for the study, you must:

Have adult diabetes
Be between 40 and 90 years of age
Not currently smoke
Not currently take a cholesterol medicine

Other exclusions may apply. Compensation is provided. To see if you qualify, call 410-550-HART or 410-550-4328.

Protocol # NA_00002253
Principal Investigator: Harry A. Silber, M.D., Ph.D.
08.27.2008

3. Do You Have Diabetic Neuropathy?
If you are 18-65 years old and a Type 1 or 2 diabetic suffering from moderate to severe burning, shocking, piercing or throbbing pain in your feet, you may qualify for a research study to evaluate the effectiveness of an investigational drug for painful diabetic peripheral neuropathy.

All office visits, medical evaluations and study drugs related to the study will be provided at no cost to participants.

Participants will be compensated for time and travel.

For more information, contact Nate Sweeney at 443-287-0589 or e-mail nsweene1@jhmi.edu.

PI: Michaels Polydefkis
RPN: NA_00010088
11.18.2008

4. VOLUNTEERS NEEDED FOR A RESEARCH STUDY ON TYPE 2 DIABETES AND SLEEP APNEA
To participate, you must be aged 18 years or older and have Type 2 diabetes. Participation will involve several clinical visits. Testing will include a sleep evaluation, an overnight sleep study, and monitoring of glucose and blood pressure. Participants will be compensated for your participation.

For more information or to participate, please contact Kelly Devine, RN, at 410-550-4891 or Melissa Minotti at 301-791-1847.

Principal Investigator: Naresh Punjabi, MD, Ph.D.
Protocol Number: NA_00019967
11.13.2008

5. Research Volunteers Needed
A study is being performed to evaluate changes in blood glucose and heart function before and after weight loss following bariatric surgery. Men and women, ages 21 to 65, are needed to participate.

The study involves 22 outpatient visits over the course of two years. Participants will be eligible for compensation up to $2,500.

For more information, please call 410-550-9278.

Principal Investigator: Dariush Elahi, Ph.D.
Protocol Number: NA_00004876
03.02.2009

6. Are You Wearing An Insulin Pump?
Men and women, ages 18 to 75, are needed for a study to find out in pancreatic polypeptide (PP), a hormone that is naturally produced by the pancreas, will reduce the amount of insulin required.

The study involves four outpatient visits over the course of six weeks. Participants could earn up to $250.

Principal Investigator: Dariush Elahi, Ph.D.
Protocol Number: NA_00010957
03.02.2009

7. Pancreatic Resections or Pancreas/Islet Transplant
Men and women, ages 18 to 80, are needed for a study to evaluate the response of the body to insulin (the hormone that naturally regulates blood sugar levels) and the response of pancreas/islet (insulin producing organ) to a sugar challenge and to a glucagon-like peptide-1 (GLP-1), a hormone that is released from the gut.

The study involves 28 outpatient visits over the course of five years. Participants could earn up to $2,475.

Principal Investigator: Dariush Elahi, Ph.D.
Protocol Number: NA_00016686
03.02.2009

8. Do You Have Diabetes?
Researchers at Johns Hopkins are seeking individuals between the ages of 20 and 75 with Type 2 diabetes who are stable on diet and exercise alone (or who take only metformin) to participate in a research project that studies an investigational diabetes medicine.

For more information, contact the Clinical Trials Unit at 410-502-3686 or e-mail myep1@jhmi.edu.

PI: Adrian S. Dobs, M.D., MHS
Protocol #: NA_00031074
10.27.2009

Drug/Alcohol Use

1. Are You a Teenager Who Has Problems With ADHD and Uses Drugs or Alcohol?
Call to find out about a research study using study pills and counseling. You will receive assessments, study pills and therapy at no cost (no insurance needed).

You may be eligible if you are between the ages of 13 and 18. You will earn payment for participation!

For more information, please call 1-877-453-3399 or 410-233-1400, ex. 172.

PI: Geetha Subramaniam, M.D.
NA_00002443
02.20.07

2. Do you use cocaine?
If so, you may be able to participate in research studies to see how drugs affect the body and brain. The studies take place in East Baltimore and are sponsored by the National Institute on Drug Abuse (NIDA), National Institutes of Health, U.S. Department of Health and Human Services.

You will be compensated for your time and travel.

Call 1-800-535-8254 from 8:30 a.m. to 8 p.m. for a confidential screening or visit www.researchstudies.drugabuse.gov.

05.21.2010

You will be compensated for your time and travel.

Call 1-800-535-8254 from 8:30 a.m. to 8 p.m. for a confidential screening or visit www.researchstudies.drugabuse.gov.

05.21.2010

4. Research Volunteers Needed for Substance Abuse Study
Healthy males and females, ages 18 to 55, with a history of substance abuse involving opiates, such as heroin or morphine, are needed for an inpatient investigational drug study at the Clinical Studies Program at Johns Hopkins Bayview Medical Center. Participants will be compensated.

For more information, please call 410-550-0185.

PI: Donald R. Jasinski, M.D.
NA_00014298
11.18.2008

5. Research on Cocaine Dependence
Are you an adult and concerned with your use of cocaine? Do you want to stop using cocaine?

A Johns Hopkins Bayview group is conducting a research study to see if an investigational medication helps treat cocaine dependence. Eligible participants will receive free study evaluations and medication. All information will be kept confidential. Compensation will be provided for time and travel.

For more information or to participate, please call 410-550-0185.

PI: Donald R. Jasinski, M.D.
NA_00011686
11.18.2008

6. Free Research Treatment for Cocaine and Opiate Abuse
Healthy men and women between the ages of 18 and 55 are needed to participate in an outpatient research study at Johns Hopkins Bayview Medical Center. The study will last up to 31 weeks and will provide standard methadone maintenance treatment.

Total possible earnings for participants are $1155.

For more information or to participate, please call 410-550-1102 and refer to study #0606.

PI: Annie Umbricht, M.D.
RPN# NA_0003333
07.29.2010

7. Marijuana Users Needed
Marijuana users, ages 18 and over, are needed to take part in a research study at Johns Hopkins.

This is NOT a treatment study. The study will involve staying at the Johns Hopkins Bayview Medical Center for approximately 7 weeks. You will be compensated for your time and cooperation.

For more information, please call 410-550-0007.

PI: Ryan Vandrey, Ph.D.
NA_00026278
03.16.2010

8. Seeking Treatment for Opiate Dependence?
Are you seeking treatment for opiate dependence? If so, you may be able to participate in research studies that provide treatment to see how best help people stop using drugs. Participants would receive counseling and either methadone or buprenorphine—and because it is research, there are no fees to pay.

The studies take place in East Baltimore and are sponsored by the National Institute on Drug Abuse (NIDA), National Institutes of Health, U.S. Department of Health and Human Services. Treatment would include counseling and probably either methadone or buprenorphine and a screening which includes a physical exam.

Call 1-866-START-NOW (1-866-782-7866) for a confidential screening or visit www.researchstudies.drugabuse.gov.

9. Cocaine Users Needed
Healthy men and women, ages 18-65, who use cocaine on a regular basis are needed to participate in a non-therapeutic research study about decision making at the Johns Hopkins Bayview Medical Center.

This study requires two sessions lasting about four hours each. Sessions will involve questions about sexual behavior. HIV and hepatitis C testing will be provided during the study.

Participants will earn $130 for completing both sessions.

For more information, please call 410-550-1916.

PI: Matthew W. Johnson, Ph.D.
NA_00027568
03.16.2010

10. Marijuana Users Needed
Marijuana users, ages 18-55, are needed to take part in a research study at Johns Hopkins.

This is NOT a treatment study. The study will last for 62 days and will involve staying at the Johns Hopkins Bayview Medical Center for 41 nights. You will be compensated for your time and cooperation.

For more information, please call 410-550-0007.

PI: Ryan Vandrey, Ph.D.
NA_00017909
07.29.2010

11. Seeking Hallucinogen Users Interested in Spirituality and Altered States of Conciousness
In recent years, scientists at some U.S. universities have been conducting studies using hallucinogens, resuming research in pharmacology, psychology, creativity and spirituality that was suspended following the drug excesses of the 1960s.

Hallucinogens have been used for centuries in sacramental contexts in order to induce non-ordinary states of consiousness for spiritual purposes. Examples include the mescaline-containing peyote cactus used by the Native American Church, psilocybin-containing mushrooms uses as sacraments in Mesoamerica, and the DMT-containing ayahuasca used by various religious groups in South America.

A lesser-known hallucinogen, Salvia divinorum, is an herb in the Sage family that has been used as a sacrament by the Mazatec people of Oaxaca, Mexico for hundreds of years. Recently, Salvia divinorum has also been used by hallucinogen users in the United States and other countries.

Researchers at the Johns Hopkins University are seeking volunteers who have used Salvia divinorum and other hallucinogens (for example, LSD or psilocybin mushrooms) to participate in a research study of states of conciousness brought about by the active principle constituent of Salvia divinorum (salvinorin A) given by inhalation, in a comfortable, supportive setting. Questionnaires and interviews will be used to assess the effects of the substance on consciousness, mood and behavior.

Volunteers enrolled in the study will receive careful preparation and up to 21 visits in which they will receive salvinorin A or placebo. Structure guidance will be provided during the sessions and afterwards to facilitate integration of the experiences. The research study complies with FDA regulations and is open to men and women.

Volunteers must be between the ages of 21 and 65, have no personal history of severe psychiatric illness, and must live within travel distance of the Hopkins Bayview campus in Baltimore.

If you would like to discuss the possibility of volunteering, please call 410-550-5990 and ask for Mary, the study's research coordinator. Confidentiality will be maintained for all applicants and participants.

PI: Roland R. Griffiths, Ph.D.
Protocol: NA_00009081
07.29.2010

12. Have You Used Methamphetamine?
Methamphetamine users are needed for a medical research study. Volunteers should be between the ages of 18-45, in good general health and taking no regular medications. Testing will take place at the Johns Hopkins Bayview Medical Center and the Johns Hopkins Hospital in Baltimore, MD.

Volunteers will be paid for completion of all study procedures. Travel expenses will be covered. Please call 410-550-2588 or 410-550-5295 or e-mail johnshopkins.lab@gmail.com for more information.

Principal Investigator: Una D. McCann
IRB Number: NA_00031313
05.21.2010

13. Do you use marijuana?
If so, you may be able to participate in research studies to see how drugs affect the body and brain. The studies take place in East Baltimore and are sponsored by the National Institute on Drug Abuse (NIDA), National Institutes of Health, U.S. Department of Health and Human Services.

You will be compensated for your time and travel.

Call 1-800-535-8254 from 8:30 a.m. to 8 p.m. for a confidential screening or visit www.researchstudies.drugabuse.gov.

05.21.2010

14. Do you use ecstacy?
If so, you may be able to participate in research studies to see how drugs affect the body and brain. The studies take place in East Baltimore and are sponsored by the National Institute on Drug Abuse (NIDA), National Institutes of Health, U.S. Department of Health and Human Services.

You will be compensated for your time and travel.

Call 1-800-535-8254 from 8:30 a.m. to 8 p.m. for a confidential screening or visit www.researchstudies.drugabuse.gov.

05.21.2010

15. Research Volunteers
Research volunteers are needed who:

Have heroin or prescription drug dependence
Do not use any other drugs
Are in otherwise good health
Want detox

If you meet the above criteria and are willing to stay on a research unit for two months, you could earn up to $1,880.

For more information, call 410-550-0007. Ask for study #1003.

PI: Eric C. Strain, M.D.
NA_00031896
07.28.2010

16. Are You Addicted to Heroin or Prescription Pain Medications?
If you are 18-65 years old and you are currently addicted to heroin or prescription pain medications, you may be interested in learning more about a new clinical research study.

The Johns Hopkins University is conducting a clinical research study to evaluate an investigational new treatment for opiate addiction. If you qualify, you will receive study-related care at no cost and may earn up to $2,100.

If you are interested in participating in this study and would like more information, please call 410-550-5250.

PI: George Bigelow
NA_00037248
07.29.2010

Fibromyalgia

1. Fibromyalgia Research Study
Researchers at The Johns Hopkins University School of Medicine are conducting a study to look at the effects of a new way to increase the physical activity of adults with fibromyalgia.

Participants will take part in group meetings and either a home-based physical activity or education program for three months. The study also requires completion of periodic assessments throughout this 18-month study. Ideally, participants will be inactive and suffering with fibromyalgia. They will not have to take any medications or change current medications during the study.

For more information, please call 410-550-8248. Enrollment is limited!

PI: Kevin Fontaine, Ph.D.
NA_00003328
11.18.2008

Hair Restoration

1. Seeking Subjects for Hair Restoration Study
Are you between the ages of 18 and 80 and concerned about hair loss on the scalp? We are currently enrolling subjects in a hair restoration study at Johns Hopkins Bayview Medical Center. If you have never had a hair restoration procedure and you are interested in participating you are encouraged to contact Lisa Earnest, M.D. at the number listed below for further information. Procedures will be provided at a 50% discount.

Contact number: 410-550-2368
PI: Lisa Earnest, M.D.
RPN #: NA_00009638
08.27.2008

Healthy Volunteers

1. Seeking Persons Committed to Spiritual Development to Participate in a Study of Mystical Experience, Meditation and Spiritual Practice
Researchers at The Johns Hopkins University School of Medicine are seeking volunteers who have an active interest in exploring and developing their spiritual lives to participate in a scientific study of the combined efforts of meditation, spiritual practice and the entheogen psilocybin, a psychoactive substance found in mushrooms used as a sacrament in some cultures.

The study will take place over six-eight months during which volunteers will be encouraged to initiate or maintain daily meditation and spiritual awareness practices. Volunteers will also receive careful preparation and 2-3 sessions in which they will receive psilocybin in a comfortable, supportive setting. Structured guidance will be provided during the session and afterwards to facilitate integration of the experiences.

For more detailed information about the study, visit bpru.org/spritual-practice. If you would like to discuss the possibility of volunteering, please call 410-550-5990 or e-mail spiritual-practice@bpru.org and ask for Mary, the study coordinator. Confidentiality will be maintained for all applicants and participants.

PI: Roland R. Griffiths, Ph.D.
Protocol: NA_00020767
07.29.2010

2. Healthy Individuals Needed
The goal of this study is to gain a better understanding of schizophrenia. We are seeking to compare individuals without schizophrenia to individuals who do have schizophrenia.

To be considered for the study, you must:

Be between the ages of 14-60 years old;
Be willing to have a blood sample drawn;
Be willing to provide a urine sample to test for drugs of abuse;
Have no history of stroke, brain tumor or serious brain injury;
Not consume alcohol or street drugs daily; and
Speak English.

Participation in the study involves:

Release of medical records;
Blood and urine sample; and
Clinical interview.

Participants will be paid $50 for their time. If you or someone you know might be interested in the study or have questions about the study, please call Nadine Yoritomo, RN, at (410) 502-5887 or e-mail schizophrenia@jhmi.edu.

PI: Russell Margolis, M.D.
RPN # NA_00009162
12.14.09

3. There May Be a Research Study For You
The National Institute on Drug Abuse (NIDA) conducts research studies to find out how various drugs, including nicotine, affect the body, the brain and behavior. There are several research opportunities for volunteers who do not smoke cigarettes or use drugs of any kind. Your part in a NIDA research study could help us better understand how the healthy brain works and how to prevent and treat drug abuse and addiction. If you are interested in volunteering as a healthy control in a NIDA research study, please call the number below. All participants will be paid for time and travel. The studies take place in the Baltimore area and are sponsored by NIDA, National Institutes of Health and the U.S. Department of Health and Human Services.

You will be compensated for your time and travel.

Call 1-800-535-8254 from 8:30 a.m. to 8 p.m. for a confidential screening or visit www.researchstudies.drugabuse.gov.

05.21.2010

Heart Disease/Cholesterol

1. Study Participants Needed
Recent studies show that some patients still are afflicted with heart disease despite having high levels of HDL cholesterol. Our main focus is how the HDL receptor, scanvenger receptor class B type 1 (SR-B1), might have a role in this problem. With this study, we hope to understand why this occurs by trying to delineate the relationship between high incidences in heart disease and decreased expression of SR-B1.

Patients that meet our enrollment criteria will donate blood at the time of enrollment and have a carotid doppler performed. We are interested in recruiting patients who meeting the following criteria:

18-80 years old
HDL more than or equal to 60 mg/Dl
not on cholesterol-lowering medications

Compensation will include copies and records (e.g. lab test results, etc.) of all health information at request, parking vouchers and $50 at the time of completion.

For more information, please contact Angela Green at 410-550-6397 or agreen6@jhmi.edu.

PI: Annabelle Rodriguez, M.D.
Protocol: HBV03-06-26-01 and 03-11-25-10
03.14.2007

2. Volunteers Needed
We are studying whether Alpha Lipoic acid, a potent antioxidant and over-the-counter product, reduces blood levels of markers of inflammation in the blood vessels when compared with placebo. Placebo is a substance that looks like the real product, but contains no active product. There will be up to six visits in 12 weeks. Blood tests will be done to check glucose and cholesterol levels to help determine your study eligibility.

Inclusions:

Male or female, aged 40 to 80 years
If female, you must be post-menopausal or sterilized and not be on hormone therapy
In addition, you must have at least three of the following conditions:
- Controlled diabetes, but not taking medication
- Moderately overweight
- Stable high blood pressure
- High cholesterol, but are not taking a statin medication

Exclusions:

Current or recent smoking
Previous heart attack or stroke
Some medications or other medical conditions may exclude you from participating

Compensation is available. For more information or to participate in the study, please call 410-550-HART (4278).

PI: Pamela Ouyang, MBBS
NA_00016646
04.20.2009

Sleep

1. VOLUNTEERS NEEDED FOR A RESEARCH STUDY ON TYPE 2 DIABETES AND SLEEP APNEA
To participate, you must be aged 18 years or older and have Type 2 diabetes. Participation will involve several clinical visits. Testing will include a sleep evaluation, an overnight sleep study, and monitoring of glucose and blood pressure. Participants will be compensated for your participation.

For more information or to participate, please contact Kelly Devine, RN, at 410-550-4891 or Melissa Minotti at 301-791-1847.

Principal Investigator: Naresh Punjabi, MD, Ph.D.
Protocol Number: NA_00019967
11.13.2008

Smoking

1. Do You Have Emphysema, Chronic Bronchitis or COPD?
If you suffer from chronic bronchitis, emphysema, smoker's lung or symptoms that include smoker's cough or other persistant coughing, shortness of breath and increased mucus or phlegm production, you may have chronic obstructive pulmonary disease (COPD). And, you're invited to participate in a new medical research study.

Qualified participants will receive study-related medication including an inhaler for their symptoms, medical exams, lab tests and financial compensation for time and travel.

To find out if you qualify, contact Candy at 410-550-9825.

PI: Mark C. Liu, M.D.
08.27.2008

2. Do you smoke cigarettes?
If so, you may be able to participate in research studies to see how smoking affects the body and brain. The studies take place in East Baltimore and are sponsored by the National Institute on Drug Abuse (NIDA), National Institutes of Health, U.S. Department of Health and Human Services.

You will be compensated for your time and travel.

Call 1-800-535-8254 from 8:30 a.m. to 8 p.m. for a confidential screening or visit www.researchstudies.drugabuse.gov.

07.06.2009

3. Cigarette Smokers Interested in a Spiritual Approach to Quitting Smoking
The Johns Hopkins University School of Medicine is seeking smokers who want to quit smoking to participate in a scientific study of spiritual/mystical experience brought about by psilocybin, a psychoactive etheogen (roughly meaning God-evoking substance) found in mushrooms used as a sacrament in some cultures, given in a comfortable, supportive setting.

Some studies have suggested that entheogens, when administered under interpersonally supportive and well-prepared conditions, are effective in helping people overcome addictions. Cognitive behavior therapy and ongoing interpersonal support will be integrated with psilocybin sessions in order to help participants quit smoking.

Questionaires, interviews and biological measures of smoking will be used to assess the treatment's effects on consciousness, mood and smoking. Volunteers enrolled in the study will receive careful preparation and three sessions in which they will receive psilocybin. Structured guidance will be provided during the sessions and afterwards to facilitate integration of the experiences. The study complies with FDA regulations.

Volunteers must be between 21 and 65 years of age, have no personal history of severe psychiatric illness or recent history of alcoholism or drug abuse, have someone willing to pick them up and drive them home at the end of the two psilocybin sessions (around 5 p.m.), and must live within travel distance of the Johns Hopkins Bayview campus.

If you would like to discuss the possibility of volunteering, please call 410-550-5990 and ask for Mary. Confidentiality will be maintained for all applicants and participants.

PI: Matthew W. Johnson, Ph.D.
Protocol: NA_00016166
03.16.2010

4. R U A TEEN SMOKER?
If you are 13-17, you may be able to participate in research studies to see how smoking affects behavior and mood. The studies take place in East Baltimore and are sponsored by the National Institute on Drug Abuse, (NIDA), part of the National Institutes of Health and the U.S. Department of Health and Human Services.

If you qualify, you will need to bring a parent or guardian to the first study visit. Participants and their parents/guardians will be paid for time and travel. There is no cost for participation or study-related tests.

Call 1-888-565-6676 for a confidential screening or visit www.researchstudies.drugabuse.gov for more information.

5. Smokers Needed
Are you thinking about trying to quit smoking in the near future? Smokers, ages 18 and over, are needed for a research study at Johns Hopkins that involves an FDA-approved medication and practice quit attempt.

Participation requires 11 visits to the Johns Hopkins Bayview Medical Center over the span of five weeks. Participants will be completed for their time and cooperation.

For more information or to participate in the study, please call 410-550-1206.

PI: Maxine Stitzer, Ph.D.
NA_00019900
07.29.2010

6. Trying to Quit Smoking?
Healthy volunteers are needed for a research study to test an investigational vaccine designed to help people quit smoking.

To qualify, you must be age 18 or over and be able to come to the Johns Hopkins Bayview Medical Center for study visits. You will be compensated for your time and cooperation.

For more information or to join the study, please call 410-550-9497 or visit jhusmokestudy.org for details.

PI: Maxine Stitzer, Ph.D.
NA_00027262
07.29.2010

Vaccines

1. Influenza Vaccine Study
The Division of Geriatric Medicine and Gerontology is looking for individuals, either between ages 18 and 74, or ages 75 and older, to participate in an influenza vaccination study that will evaluate immune function in older adults.

To determine whether you are eligible for the study, we will ask some questions about your health over the phone. If you are eligible and agree to participate, you will receive a brief history and physical exam by a doctor, as well as the influenza vaccine (flu shot). You also be asked to donate blood samples before and after the "flu shot." We will follow up with you by phone to check on how you're doing throughout the flu season (usually lasts until the end of April).

For more information, please contact the study coordinator at 410-550-2113.

PI: Sean X. Leng, M.D., Ph.D.
NA_00004478
11.24.2008

Vascular Disease

1. NIH-Sponsored Peripheral Arterial Disease (PAD) Clinical Trial Recruiting Patients at Johns Hopkins Bayview
Peripheral arterial disease (PAD) is a major source of morbidity and mortality, particularly in older individuals. Claudication (leg pain with walking, typically relieved with rest) may be a symptom of PAD.

Claudication: Exercise Versus Endoluminal Revascularization (CLEVER) is a prospective, randomized, multicenter clinical trial designed to determine optimal treatment for claudication due to aortoiliac disease. It compares the benefits of supervised exercise, endovascular revascularization and optimal medical care.

Who may be eligible: Age 40 and older with intermittent claudication due to aortoiliac peripheral arterial disease

If you are interested in learning more about this research study or if you have a patient who may be eligible, please call the Johns Hopkins Center for Vascular Medicine at 410-955-5897 or e-mail eratchf1@jhmi.edu.

PI: Elizabeth Ratchford, M.D.
NA_00015857
04.20.2009

2. Venous Leg Ulcers
Do you have venous stasis disease? Do you have a leg ulcer? Johns Hopkins Wound Center is conducting a research study on venous leg ulcers using an advanced biologic skin repair therapy.

Patients with six-week to two-year-old venous leg ulcers are needed to participate in the study. Participants would come to the wound clinic at Johns Hopkins Bayview on a weekly basis for spray application of study skin cells and free comprehensive wound care, including dressings, pressure wraps and shoes.

Study participants will be compensated $35 per visit. Approximately 15 visits are required.

For more information or to find out in you're eligible to participate, please contact Yolanda Johnson at 410-550-4724.

PI: Gerald Lazarus, M.D.
NA_00027356
09.28.09

Women's Health

1. Do You Have Vulvodynia?
You may be eligible to participate in a research study on an experimental topical medication.

To participate in this study, you must:

be a woman between ages 18 and 55;
be in generally good health; and,
have had vulvar pain for more than three months.

Subjects will be compensated for time and travel.

For more information, call 410-550-3064.

PI: Anne Burke, M.D., MPH
RPN #: NA_00002970
08.27.2008

2. The HIP Study
If you are a woman 35-60 years of age, you may be eligible to participate in The HIP Study.

The HIP Study is a research project designed to learn more about human papillomavirus (HPV) infection in women as they transition through menopause.

Enrollment is taking place at participating clinics in the following locations: The Johns Hopkins Hospital, Johns Hopkins Bayview Medical Center, Johns Hopkins at Greenspring Station and Johns Hopkins at White Marsh.

The study requires five clinic visits. Subjects will be compensated upon completion of the study.

For more information, visit our Web site (www.jhsph.edu/HIPstudy), e-mail hipstudy@jhsph.edu or call 410-955-4203.

PI: Patti Gravitt, PhD
Protocol: NA_0000078
10.27.2009

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