Assistant Professor, Surgery
Director, Endovascular Surgery
Contact Information and Appointments
410-550-4335 phone firstname.lastname@example.org
- Cerebral Vascular Disease
Carotid endarterectomy with evoked potential neurological monitoring
Carotid angioplasty/stenting under cerebral protection
- Aortic Aneurysm Disease
Open repair of abdominal aortic aneurysm
Endovascular repair of abdominal aortic aneurysm (EVAR)
Endovascular repair of thoracic aortic aneurysm (TEVAR)
Endovascular repair of aortic dissection
- Perpheral Arterial Disease
Medical management of intermittent claudication (calf pain with walking)
Minimally invasive angioplasty and stenting
Limb salvage revascularization with open bypass surgery (for gangrene and leg pain at rest)
- Renal Artery Disease
Renal artery angioplasty and stenting for uncontrollable hypertension
Renal artery bypass
- Mesenteric Ischemia (pain after eating and weight loss from blockage in the main artery feeding the bowel)
Angioplasty and stenting in the superior mesenteric artery
Mesenteric artery bypass
- Subclavian Steal Syndrome (subclavian artery stenosis causing dizzy spells and arm pain)
Minimally invasive angioplasty and stenting
Subclavian artery bypass
- Venous Insufficiency (varicose vein and non-healing ulcers)
Minimally invasive radiofrequency ablation
- treatment of carotid artery stenosis and stroke
- renal protection for angioplasty and stenting
- clinical outcomes analysis
- minimally invasive endovascular aneurysm repair
- device development and complications prevention
- molecular biology of intimal hyperplesia and cryopreserved veins grafts
- drug-eluting stents to treat lower extremity arterial stenosis
- CREST: Principle investigator. This is a multi-center prospective,
randomized trial comparing the gold standard carotid endarterectomy vs.
the minimally-invasive carotid stenting under cerebral protection to treat
carotid artery stenosis and prevent stroke. The study is sponsored by
the National Institute of Health (NIH) and National Institute of
Neurological Disorders and Stroke (NINDS).
- CAPTURE II: Principle investigator. This is a prospective, multi-center,
post-market trial for the FDA-approved carotid devices, RX Acculink® and
RX Accunet™ (Guidant system). The purpose of this study is to provide
additional information on how the devices can be used safely by a wide
range of physicians under commercial use conditions and identify rare or
unanticipated device-related events.
- CHOICE: Principle investigator. This is a prospective, multi-center,
descriptive, post-market study of two carotid artery stent systems and
two embolic protection systems (RX Acculink® and RX Accunet™, and
Xact®, Emboshield® and BareWire™) among high-surgical-risk patients
with carotid artery disease.
- SAPPHIRE WW: Principal investigator. This is a multi-center,
prospective, observational study of 30-day Major Adverse Event (MAE)
(any death, stroke or MI) with distal protection in the treatment of
obstructive carotid artery stenosis in high-surgical-risk patients with
atherosclerotic disease of the carotid artery. The devices utilized are
the PRECISE® and ANGIOGUARD™ XP (Cordis system).
- ROBUST: Principal investigator. This is a prospective, randomized
study comparing open bypass vs. angioplasty and stenting of the lower
extremity in TASC II B and C lesions of the superficial femoral artery.
The study aims to identify the patancy and limb salvage rate, quality of
life and walking distance improvement as well as the morbidities
associated with each treatment modality.
- PRICELESS: Principle investigator. This multi-center, prospective trial
uses EndoSure® by CardioMEMS, Inc., an FDA-approved wireless device for measuring of intrasac pressure during endovascular abdominal
aortic aneurysm (AAA) repair and endovascular thoracic aneurysm repair (TAA). The purpose of the study is to identify the efficacy of this system
in predicting endoleak and aneurysm rupture in comparison to the traditional
Contrast Tomography and Arterial Duplex Ultrasound.
- ZILVER PTX: Principle investigator. This is a phase-2, prospective,
randomized study to evaluate the patancy rate of the drug-eluting Zilver
PTX™ stent vs. bare metal Zilver stent (Cook, Inc.) in the above-the-knee
- PYTHAGORAS: Principle investigator. This trial is intended to demonstrate
the safety and efficacy of the Aorfix endovascular stent graft (Aorfix™), by
Lombard Medical, in the treatment of abdominal aortic, aorto-iliac and
common iliac aneurysms with necks of up to 90 degrees.
- JOHNS HOPKINS VASCULAR REGISTRY: Principle investigator. This is a
registry of vascular patients at The Johns Hopkins Institutions. The registry
will provide useful clinical and non-clinical data for future studies.
Mahmoud B. Malas, M.D., joined the Johns Hopkins surgical faculty in 2005. He received general surgery training at the University of Southern California and completed a fellowship in vascular and endovascular surgery at the Montefiore Medical Center (Albert Einstein College of Medicine in New York).
Malas focuses his research and clinical practice on minimally-invasive endovascular repair of abdominal, thoracic and peripheral aneurysms, aortic dissection, angioplasty and stenting of (1) the carotid artery with cerebral protection to prevent stroke, (2) the renal artery with filter protection to prevent renal failure and treat intractable hypertension, (3) the subclavian artery to treat steal syndrome and (4) the lower extremity arteries for limb salvage and to treat intermittent claudication.
He also specializes in the traditional open vascular repair of aneurysms, lower extremities bypass and carotid endarterectomy, and provides comprehensive assessment of venous disease, including varicose veins and chronic venous insufficiency. Malas offers the latest minimally-invasive methods in treating these conditions with laser and radiofrequency ablation of veins.